4L9M
Autoinhibited state of the Ras-specific exchange factor RasGRP1
Summary for 4L9M
Entry DOI | 10.2210/pdb4l9m/pdb |
Descriptor | RAS guanyl-releasing protein 1, CITRIC ACID, GLYCEROL, ... (5 entities in total) |
Functional Keywords | ras nucleotide exchange factor, signaling protein |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm, cytosol: O95267 |
Total number of polymer chains | 1 |
Total formula weight | 64627.63 |
Authors | Iwig, J.S.,Vercoulen, Y.,Das, R.,Barros, T.,Limnander, A.,Che, Y.,Pelton, J.G.,Wemmer, D.E.,Roose, J.P.,Kuriyan, J. (deposition date: 2013-06-18, release date: 2013-08-21, Last modification date: 2023-09-20) |
Primary citation | Iwig, J.S.,Vercoulen, Y.,Das, R.,Barros, T.,Limnander, A.,Che, Y.,Pelton, J.G.,Wemmer, D.E.,Roose, J.P.,Kuriyan, J. Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife, 2:e00813-e00813, 2013 Cited by PubMed: 23908768DOI: 10.7554/eLife.00813 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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