4L5J

Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition

4L5J の概要

• エントリーDOI: 10.2210/pdb4l5j/pdb
• 関連するPDBエントリー: 4L4Y 4L4Z 4L50 4L51 4L5I
• 分子名称: Transcriptional regulator LsrR, 5-O-phosphono-alpha-D-ribofuranose (3 entities in total)
• 機能のキーワード: dna transcriptional regulator, phospho-ai-2 binding, dna binding, transcription regulator, sorc/deor family, helix-turn-helix domain
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 136587.80

構造登録者

Ryu, K.S.,Ha, J.H.,Eo, Y. (登録日: 2013-06-11, 公開日: 2013-11-06, 最終更新日: 2024-02-28)

• 主引用文献: Ha, J.H.,Eo, Y.,Grishaev, A.,Guo, M.,Smith, J.A.,Sintim, H.O.,Kim, E.H.,Cheong, H.K.,Bentley, W.E.,Ryu, K.S.; Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition.; J.Am.Chem.Soc., 135:15526-15535, 2013; PubMed: 24047255; DOI: 10.1021/ja407068v

実験手法

X-RAY DIFFRACTION (2.6 Å)