4L5I
Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition
Summary for 4L5I
Entry DOI | 10.2210/pdb4l5i/pdb |
Related | 4L4Y 4L4Z 4L50 4L51 4L5J |
Descriptor | Transcriptional regulator LsrR (1 entity in total) |
Functional Keywords | dna transcriptional regulator, phospho-ai-2 binding, dna binding, transcription regulator, sorc/deor family, helix-turn-helix domain |
Biological source | Escherichia coli |
Cellular location | Cytoplasm (Potential): P76141 |
Total number of polymer chains | 4 |
Total formula weight | 135667.36 |
Authors | |
Primary citation | Ha, J.H.,Eo, Y.,Grishaev, A.,Guo, M.,Smith, J.A.,Sintim, H.O.,Kim, E.H.,Cheong, H.K.,Bentley, W.E.,Ryu, K.S. Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition. J.Am.Chem.Soc., 135:15526-15535, 2013 Cited by PubMed: 24047255DOI: 10.1021/ja407068v PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.21 Å) |
Structure validation
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