4KXF
Crystal structure of NLRC4 reveals its autoinhibition mechanism
Summary for 4KXF
Entry DOI | 10.2210/pdb4kxf/pdb |
Descriptor | NLR family CARD domain-containing protein 4, ADENOSINE-5'-DIPHOSPHATE, SULFATE ION (3 entities in total) |
Functional Keywords | auto-inhibition, muti-domain, innate immunity, phosphorylation, adp binding, immune system |
Biological source | Mus musculus (mouse) |
Cellular location | Cytoplasm, cytosol: Q3UP24 |
Total number of polymer chains | 8 |
Total formula weight | 939337.61 |
Authors | |
Primary citation | Hu, Z.,Yan, C.,Liu, P.,Huang, Z.,Ma, R.,Zhang, C.,Wang, R.,Zhang, Y.,Martinon, F.,Miao, D.,Deng, H.,Wang, J.,Chang, J.,Chai, J. Crystal structure of NLRC4 reveals its autoinhibition mechanism Science, 341:172-175, 2013 Cited by PubMed: 23765277DOI: 10.1126/science.1236381 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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