4KXF

Crystal structure of NLRC4 reveals its autoinhibition mechanism

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	K, B, D, F, H...	NLR family CARD domain-containing protein 4	polymer	1024	116966.0	8	UniProt (Q3UP24) Pfam (PF00619) Pfam (PF05729) Pfam (PF22524) Pfam (PF17889) In PDB	Mus musculus (mouse)	Caspase recruitment domain-containing protein 12, Ice protease-activating factor, Ipaf
2	K, B, D, F, H...	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	8	Chemie (ADP)
3	B, N	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	935727.9
Non-Polymers*	Number of molecules	10
	Total formula weight	3609.7
All*	Total formula weight	939337.6

*Water molecules are not included.