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4KXF

Crystal structure of NLRC4 reveals its autoinhibition mechanism

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(K, B, D, F, H...)
NLR family CARD domain-containing protein 4polymer1024116966.08UniProt (Q3UP24)
Pfam (PF00619)
Pfam (PF05729)
Pfam (PF22524)
Pfam (PF17889)
Mus musculus (mouse)Caspase recruitment domain-containing protein 12, Ice protease-activating factor, Ipaf
2I, J, L, M, N...
(K, B, D, F, H...)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.28Chemie (ADP)
3K, Q
(B, N)
SULFATE IONnon-polymer96.12Chemie (SO4)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight935727.9
Non-Polymers*Number of molecules10
Total formula weight3609.7
All*Total formula weight939337.6
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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