4KVG

Crystal structure of RIAM RA-PH domains in complex with GTP bound Rap1

4KVG の概要

• エントリーDOI: 10.2210/pdb4kvg/pdb
• 分子名称: Ras-related protein Rap-1A, Amyloid beta A4 precursor protein-binding family B member 1-interacting protein, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: ras-related protein, ubiquitin fold, gtpase, actin polymerization, integrin activation, cell adhesion, riam, rapl, mst1, pdk, rap1, ena/vasp, profilin, membrane, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Lipid-anchor: P62834; Cell membrane; Peripheral membrane protein: Q8R5A3
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 101497.81

構造登録者

Zhang, H.,Chang, Y.E.,Brennan, M.L.,Wu, J. (登録日: 2013-05-22, 公開日: 2014-03-05, 最終更新日: 2024-02-28)

• 主引用文献: Zhang, H.,Chang, Y.C.,Brennan, M.L.,Wu, J.; The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism.; J Mol Cell Biol, 6:128-139, 2014; PubMed: 24287201; DOI: 10.1093/jmcb/mjt044

実験手法

X-RAY DIFFRACTION (1.65 Å)