4KSD

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

4KSD の概要

• エントリーDOI: 10.2210/pdb4ksd/pdb
• 関連するPDBエントリー: 4KSB 4KSC 4LSG
• 分子名称: Multidrug resistance protein 1A, R2 protein (2 entities in total)
• 機能のキーワード: transporter, atp binding, membrane, membrane protein, transport protein
• 由来する生物種: Mus musculus (mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 155687.16

構造登録者

Ward, A.,Szewczyk, P.,Grimard, V.,Lee, C.-W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.,Urbatsch, I.,Govaerts, C.,Steyaert, J.,Chang, G. (登録日: 2013-05-17, 公開日: 2013-07-31, 最終更新日: 2019-07-17)

• 主引用文献: Ward, A.B.,Szewczyk, P.,Grimard, V.,Lee, C.W.,Martinez, L.,Doshi, R.,Caya, A.,Villaluz, M.,Pardon, E.,Cregger, C.,Swartz, D.J.,Falson, P.G.,Urbatsch, I.L.,Govaerts, C.,Steyaert, J.,Chang, G.; Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain.; Proc.Natl.Acad.Sci.USA, 110:13386-13391, 2013; PubMed: 23901103; DOI: 10.1073/pnas.1309275110

実験手法

X-RAY DIFFRACTION (4.1001 Å)