4KMP

Structure of XIAP-BIR3 and inhibitor

Summary for 4KMP

• Entry DOI: 10.2210/pdb4kmp/pdb
• Related: 4KMN
• Descriptor: E3 ubiquitin-protein ligase XIAP, ZINC ION, (2S,2'S)-N,N'-[(6,6'-difluoro-1H,1'H-2,2'-biindole-3,3'-diyl)bis{methanediyl[(2R,4S)-4-hydroxypyrrolidine-2,1-diyl][(2S)-1-oxobutane-1,2-diyl]}]bis[2-(methylamino)propanamide], ... (4 entities in total)
• Functional Keywords: apoptosis, xiap-bir3, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P98170
• Total number of polymer chains: 2
• Total formula weight: 23557.14

Authors

Li, X.,Wang, J.,Condon, S.M.,Shi, Y. (deposition date: 2013-05-08, release date: 2014-05-14, Last modification date: 2023-11-08)

• Primary citation: Li, X.,Wang, J.,Condon, S.M.,Shi, Y.; Structure of XIAP-BIR3 and inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)