4KMN

Structure of cIAP1-BIR3 and inhibitor

Summary for 4KMN

• Entry DOI: 10.2210/pdb4kmn/pdb
• Related: 4KMP
• Descriptor: Baculoviral IAP repeat-containing protein 2, ZINC ION, (2S)-N-{(2R)-1-[(2R,4S)-2-{[6,6'-difluoro-3'-({(2R,4S)-4-hydroxy-1-[(2S)-2-{[(2S)-2-(methylamino)propanoyl]amino}butanoyl]pyrrolidin-2-yl}methyl)-1H,1'H-2,2'-biindol-3-yl]methyl}-4-hydroxypyrrolidin-1-yl]-1-oxobutan-2-yl}-2-(methylamino)propanamide, ... (5 entities in total)
• Functional Keywords: apoptosis, ciap1-bir3, ligase-ligase inhibitor complex, ligase/ligase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q13490
• Total number of polymer chains: 1
• Total formula weight: 12789.70

Authors

Li, X.,Wang, J.,Condon, S.M.,Shi, Y. (deposition date: 2013-05-08, release date: 2014-05-14, Last modification date: 2023-11-08)

• Primary citation: Li, X.,Wang, J.,Condon, S.M.,Shi, Y.; Structure of cIAP1-BIR3 and inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (1.523 Å)