4KKH

The crystal structure of inhibitor-bound JNK3

Summary for 4KKH

• Entry DOI: 10.2210/pdb4kkh/pdb
• Related: 4KKE 4KKG
• Descriptor: Mitogen-activated protein kinase 10, cyclopropyl[(3R)-3-({4-[6-hydroxy-2-(naphthalen-2-yl)-1H-benzimidazol-1-yl]pyrimidin-2-yl}amino)piperidin-1-yl]methanone (3 entities in total)
• Functional Keywords: kinase domain, kinase, c-jun, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P53779
• Total number of polymer chains: 1
• Total formula weight: 42621.31

Authors

Han, B.G.,Shim, M.B.,Ahn, H.C. (deposition date: 2013-05-06, release date: 2014-05-21, Last modification date: 2024-02-28)

• Primary citation: Han, B.G.,Shim, M.B.,Ahn, H.C.; The crystal structure of AMP, apo, and inhibitor-bound JNK3; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)