4KG8

Crystal structure of light mutant

4KG8 の概要

• エントリーDOI: 10.2210/pdb4kg8/pdb
• 関連するPDBエントリー: 3K51 3MHD 3MI8 4EN0 4FHQ 4J6G
• 分子名称: Tumor necrosis factor ligand superfamily member 14 (2 entities in total)
• 機能のキーワード: structural genomics, psi-biology, new york structural genomics research consortium, nysgrc, immunity, tnf superfamily, hvem, dcr3, n-glycosylation, membrane, secreted protein, cytokine, atoms-to-animals: the immune function network, jelly-roll fold, bind tnf receptor hvem and ltbr, ltbr, protein structure initiative, ifn
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Tumor necrosis factor ligand superfamily member 14, membrane form: Cell membrane; Single-pass type II membrane protein. Tumor necrosis factor ligand superfamily member 14, soluble form: Secreted. Isoform 2: Cytoplasm: O43557
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 51625.31

構造登録者

Liu, W.,Zhan, C.,Kumar, P.R.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.,New York Structural Genomics Research Consortium (NYSGRC),Atoms-to-Animals: The Immune Function Network (IFN) (登録日: 2013-04-28, 公開日: 2013-08-07, 最終更新日: 2023-09-20)

• 主引用文献: Liu, W.,Zhan, C.,Cheng, H.,Kumar, P.R.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.; Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.; Structure, 22:1252-1262, 2014; PubMed: 25087510; DOI: 10.1016/j.str.2014.06.013

実験手法

X-RAY DIFFRACTION (2.25 Å)