4KEH

Crosslinked Crystal Structure of Type II Fatty Synthase Dehydratase, FabA, and Acyl Carrier Protein, AcpP

4KEH の概要

• エントリーDOI: 10.2210/pdb4keh/pdb
• 関連するPDBエントリー: 1MKA 2K92
• 分子名称: N-{3-[DIHYDROXY(NONYL)-LAMBDA~4~-SULFANYL]PROPYL}-N~3~-[(2R)-2-HYDROXY-3,3-DIMETHYL-4-(PHOSPHONOOXY)BUTANOYL]-BETA-ALANINAMIDE, Acyl carrier protein, N-{3-[dihydroxy(nonyl)-lambda~4~-sulfanyl]propyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, ... (4 entities in total)
• 機能のキーワード: fatty acid synthesis, protein-protein complex, dehydratase/isomerase, acyl carrier protein, isomerase-biosynthetic protein complex, isomerase/biosynthetic protein
• 由来する生物種: Escherichia coli; 詳細
• 細胞内の位置: Cytoplasm: P0A6Q3; Cytoplasm (By similarity): K0BL73
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 55813.48

構造登録者

Nguyen, C.,Haushalter, R.,Finzel, K.,Leong, J.,Le, B.C.,Burkart, M.,Tsai, S.C. (登録日: 2013-04-25, 公開日: 2013-12-25, 最終更新日: 2014-01-29)

• 主引用文献: Nguyen, C.,Haushalter, R.W.,Lee, D.J.,Markwick, P.R.,Bruegger, J.,Caldara-Festin, G.,Finzel, K.,Jackson, D.R.,Ishikawa, F.,O'Dowd, B.,McCammon, J.A.,Opella, S.J.,Tsai, S.C.,Burkart, M.D.; Trapping the dynamic acyl carrier protein in fatty acid biosynthesis.; Nature, 505:427-431, 2014; PubMed: 24362570; DOI: 10.1038/nature12810

実験手法

X-RAY DIFFRACTION (1.901 Å)