4K6U
Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386
Summary for 4K6U
| Entry DOI | 10.2210/pdb4k6u/pdb |
| Related | 1UXE 3N0I 3QND 4K6T 4K6V 4K6W |
| Descriptor | Fiber protein, ZINC ION, N-acetyl-alpha-neuraminic acid, ... (6 entities in total) |
| Functional Keywords | adenovirus, fiber knob, protein carbohydrate interaction, carbohydrate mimic, multivalent ligand, viral protein |
| Biological source | Human adenovirus 37 |
| Total number of polymer chains | 3 |
| Total formula weight | 66767.18 |
| Authors | Stehle, T.,Bauer, J. (deposition date: 2013-04-16, release date: 2014-10-22, Last modification date: 2024-04-03) |
| Primary citation | Caraballo, R.,Saleeb, M.,Bauer, J.,Liaci, A.M.,Chandra, N.,Storm, R.J.,Frangsmyr, L.,Qian, W.,Stehle, T.,Arnberg, N.,Elofsson, M. Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells. Org.Biomol.Chem., 13:9194-9205, 2015 Cited by PubMed: 26177934DOI: 10.1039/c5ob01025j PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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