3QND

crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor

Summary for 3QND

Entry DOI	10.2210/pdb3qnd/pdb
Descriptor	Fiber protein, ZINC ION, N-acetyl-alpha-neuraminic acid, ... (4 entities in total)
Functional Keywords	fiber knob, protein carbohydrate interaction, carbohydrate mimetic, multivalent ligand, viral protein-inhibitor complex, cell adhesion-inhibitor complex, cell adhesion/inhibitor
Biological source	Human adenovirus 37
Total number of polymer chains	6
Total formula weight	132612.69
Authors	Stehle, T.,Bauer, J.,Elofsson, M. (deposition date: 2011-02-08, release date: 2011-06-15, Last modification date: 2023-09-13)
Primary citation	Spjut, S.,Qian, W.,Bauer, J.,Storm, R.,Frangsmyr, L.,Stehle, T.,Arnberg, N.,Elofsson, M. A potent trivalent sialic Acid inhibitor of adenovirus type 37 infection of human corneal cells. Angew.Chem.Int.Ed.Engl., 50:6519-6521, 2011 Cited by PubMed: 21648036 DOI: 10.1002/anie.201101559 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation