4K6U
Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0386
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Fiber protein | polymer | 194 | 21716.5 | 3 | UniProt (Q64823) Pfam (PF00541) | Human adenovirus 37 | |
| 2 | D, F, I (A, B, C) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 3 | E, G, J (A, B, C) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 3 | Chemie (SIA) | |||
| 4 | H (B) | 3,3',3''-[nitrilotris(methanediyl-1H-1,2,3-triazole-4,1-diyl)]tripropan-1-ol | non-polymer | 434.5 | 1 | Chemie (1P4) | |||
| 5 | K (C) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | L, M, N (A, B, C) | water | water | 18.0 | 445 | Chemie (HOH) |
Sequence modifications
A, B, C: 177 - 365 (UniProt: Q64823)
| PDB | External Database | Details |
|---|---|---|
| Gly 172 | - | expression tag |
| Ala 173 | - | expression tag |
| Met 174 | - | expression tag |
| Gly 175 | - | expression tag |
| Ser 176 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 65149.6 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1617.6 | |
| All* | Total formula weight | 66767.2 |
