4K13

Structure of HCAIX mimic (HCAII with 5 mutations in active site) in complex with dorzolamide

Summary for 4K13

• Entry DOI: 10.2210/pdb4k13/pdb
• Related: 4K0S 4K0T 4K0Z 4K1Q
• Descriptor: Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total)
• Functional Keywords: alpha beta fold, lyase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 29446.69

Authors

Biswas, S.,McKenna, R. (deposition date: 2013-04-04, release date: 2014-04-09, Last modification date: 2023-09-20)

• Primary citation: Biswas, S.,West, D.,Pinard, M.,McKenna, R.; Developing isoform specific inhibitors for hCAIX using CAIX mimic; To be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)