4K0Z
Structure of HCAIX mimic (HCAII with 5 mutations in active site) in complex with methazolamide
Summary for 4K0Z
Entry DOI | 10.2210/pdb4k0z/pdb |
Related | 4K0S 4K0T 4K13 4K1Q |
Descriptor | Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | alpha beta fold, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29796.47 |
Authors | Biswas, S.,McKenna, R. (deposition date: 2013-04-04, release date: 2014-04-09, Last modification date: 2023-09-20) |
Primary citation | Biswas, S.,West, D.,Pinard, M.,McKenna, R. Developing isoform specific inhibitors for hCAIX using CAIX mimic To be Published, |
Experimental method | X-RAY DIFFRACTION (1.799 Å) |
Structure validation
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