4K0T

Structure of HCAIX mimic (HCAII with 5 mutations in active site) in complex with chlorzolamide

Summary for 4K0T

• Entry DOI: 10.2210/pdb4k0t/pdb
• Related: 4K0S 4K0Z 4K13 4K1Q
• Descriptor: Carbonic anhydrase 2, ZINC ION, DIMETHYL SULFOXIDE, ... (6 entities in total)
• Functional Keywords: alpha beta fold, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29490.08

Authors

Biswas, S.,McKenna, R. (deposition date: 2013-04-04, release date: 2014-04-09, Last modification date: 2023-09-20)

• Primary citation: Biswas, S.,West, D.,Pinard, M.,McKenna, R.; Designing isoform specific inhibitors against hCAIX using CAIX mimic; To be Published,

Experimental method

X-RAY DIFFRACTION (1.78 Å)