4JTJ

Crystal structure of R117K mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

Summary for 4JTJ

Entry DOI	10.2210/pdb4jtj/pdb
Related	4JTE 4JTF 4JTG 4JTH 4JTI 4JTK 4JTL
Descriptor	2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION, ... (4 entities in total)
Functional Keywords	manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, transferase, lipopolysaccharide biosynthesis
Biological source	Neisseria meningitidis
Cellular location	Cytoplasm (By similarity): Q9JZ55
Total number of polymer chains	4
Total formula weight	122094.60
Authors	Allison, T.M.,Cochrane, F.C.,Jameson, G.B.,Parker, E.J. (deposition date: 2013-03-23, release date: 2013-06-26, Last modification date: 2023-09-20)
Primary citation	Allison, T.M.,Cochrane, F.C.,Jameson, G.B.,Parker, E.J. Examining the Role of Intersubunit Contacts in Catalysis by 3-Deoxy-d-manno-octulosonate 8-Phosphate Synthase. Biochemistry, 52:4676-4686, 2013 Cited by PubMed: 23746359 DOI: 10.1021/bi400521f PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation