4JTJ

Crystal structure of R117K mutant of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	2-dehydro-3-deoxyphosphooctonate aldolase	polymer	280	30491.3	4	UniProt (Q9JZ55) Pfam (PF00793)	Neisseria meningitidis	3-deoxy-D-manno-octulosonic acid 8-phosphate synthase, KDO-8-phosphate synthase, KDO 8-P synthase, KDOPS, Phospho-2-dehydro-3-deoxyoctonate aldolase
2	E, F, H (A, C, D)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
3	G (C)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	I, J, K, L (A, B, C, D)	water	water		18.0	338	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 280 (UniProt: Q9JZ55)

PDB	External Database	Details
Lys 117	Arg 117	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	121965.3
Non-Polymers*	Number of molecules	4
	Total formula weight	129.3
All*	Total formula weight	122094.6

*Water molecules are not included.