4JQ1
AKR1C2 complex with naproxen
Summary for 4JQ1
Entry DOI | 10.2210/pdb4jq1/pdb |
Related | 4JQ2 4JQ3 4JQ4 4JQA 4JTQ 4JTR |
Descriptor | Aldo-keto reductase family 1 member C2, (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (7 entities in total) |
Functional Keywords | oxidoreductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm : P52895 |
Total number of polymer chains | 2 |
Total formula weight | 78031.33 |
Authors | Yosaatmadja, Y.,Flanagan, J.U.,Squire, C.J. (deposition date: 2013-03-19, release date: 2014-04-02, Last modification date: 2024-04-03) |
Primary citation | Yosaatmadja, Y.,Flanagan, J.U.,Squire, C.J. Structural basis of NSAID selectivity for the aldo-keto reductase 1C family To be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
Download full validation report