4JMY

Crystal structure of HCV NS3/NS4A protease complexed with DDIVPC peptide

Summary for 4JMY

• Entry DOI: 10.2210/pdb4jmy/pdb
• Descriptor: Polyprotein, HCV non-structural protein 4A, substrate peptide, ... (6 entities in total)
• Functional Keywords: hepatitis c virus, serine protease, ddivpc, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Hepatitis C virus genotype 2; More
• Total number of polymer chains: 6
• Total formula weight: 44456.10

Authors

Lemke, C.T. (deposition date: 2013-03-14, release date: 2013-10-30, Last modification date: 2024-02-28)

• Primary citation: LaPlante, S.,Lemke, C.T.; Importance of the peptide scaffold of drugs that target the hepatitis C virus NS3 protease and its crucial bioactive conformation and dynamic factors.; To be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)