4JMY
Crystal structure of HCV NS3/NS4A protease complexed with DDIVPC peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Polyprotein | polymer | 186 | 19663.6 | 2 | UniProt (Q81817) Pfam (PF02907) | Hepatitis C virus genotype 2 | |
| 2 | C, D (C, D) | HCV non-structural protein 4A | polymer | 17 | 1815.3 | 2 | UniProt (by SIFTS) (P26662) | ||
| 3 | E, F (E, F) | substrate peptide | polymer | 6 | 660.7 | 2 | |||
| 4 | G, I (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | H, J (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | K, L, M, N, O... (A, B, C, D, E...) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 180 (UniProt: Q81817)
| PDB | External Database | Details |
|---|---|---|
| Ala 181 | - | expression tag |
| Ser 182 | - | expression tag |
| Lys 183 | - | expression tag |
| Lys 184 | - | expression tag |
| Lys 185 | - | expression tag |
| Lys 186 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 44279.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 176.8 | |
| All* | Total formula weight | 44456.1 |
