4JFS
Crystal structure of a bacterial fucosidase with iminosugar inhibitor 4-epi-(+)-Codonopsinine
Summary for 4JFS
| Entry DOI | 10.2210/pdb4jfs/pdb |
| Related | 2WVV 4J27 4J28 4JFT 4JFU 4JFV 4JFW |
| Descriptor | alpha-L-fucosidase, (2S,3S,4R,5S)-2-(4-methoxyphenyl)-1,5-dimethylpyrrolidine-3,4-diol, IMIDAZOLE, ... (7 entities in total) |
| Functional Keywords | alpha-l-fucosidase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Bacteroides thetaiotaomicron |
| Total number of polymer chains | 2 |
| Total formula weight | 105696.53 |
| Authors | Wright, D.W.,Davies, G.J. (deposition date: 2013-02-28, release date: 2013-09-18, Last modification date: 2023-09-20) |
| Primary citation | Hottin, A.,Wright, D.W.,Steenackers, A.,Delannoy, P.,Dubar, F.,Biot, C.,Davies, G.J.,Behr, J.B. alpha-L-fucosidase inhibition by pyrrolidine-ferrocene hybrids: rationalization of ligand-binding properties by structural studies. Chemistry, 19:9526-9533, 2013 Cited by PubMed: 23740878DOI: 10.1002/chem.201301001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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