4JFS
Crystal structure of a bacterial fucosidase with iminosugar inhibitor 4-epi-(+)-Codonopsinine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004560 | molecular_function | alpha-L-fucosidase activity |
| A | 0005764 | cellular_component | lysosome |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006004 | biological_process | fucose metabolic process |
| A | 0016139 | biological_process | glycoside catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004560 | molecular_function | alpha-L-fucosidase activity |
| B | 0005764 | cellular_component | lysosome |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0006004 | biological_process | fucose metabolic process |
| B | 0016139 | biological_process | glycoside catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 16Z A 501 |
| Chain | Residue |
| A | HIS66 |
| A | TRP316 |
| A | GOL506 |
| A | GLU87 |
| A | TRP88 |
| A | HIS135 |
| A | TYR178 |
| A | ASP229 |
| A | TRP232 |
| A | ARG262 |
| A | GLU288 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD A 502 |
| Chain | Residue |
| A | ILE65 |
| A | TRP117 |
| A | MET120 |
| A | TYR168 |
| A | PHE359 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE IMD A 503 |
| Chain | Residue |
| A | LYS90 |
| A | PRO96 |
| A | ALA97 |
| A | HOH864 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IMD A 504 |
| Chain | Residue |
| A | ARG399 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 505 |
| Chain | Residue |
| A | ARG262 |
| A | ARG271 |
| A | HIS272 |
| A | HOH988 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 506 |
| Chain | Residue |
| A | ALA85 |
| A | GLU87 |
| A | TRP88 |
| A | TRP92 |
| A | ASN314 |
| A | 16Z501 |
| A | HOH713 |
| A | HOH1076 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 16Z B 501 |
| Chain | Residue |
| B | HIS66 |
| B | GLU87 |
| B | TRP88 |
| B | HIS135 |
| B | TYR178 |
| B | ASP229 |
| B | TRP232 |
| B | ARG262 |
| B | GLU288 |
| B | TRP316 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE IMD B 502 |
| Chain | Residue |
| B | ILE65 |
| B | TRP117 |
| B | MET120 |
| B | TYR168 |
| B | PHE359 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IMD B 503 |
| Chain | Residue |
| B | TRP241 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 504 |
| Chain | Residue |
| B | ARG262 |
| B | ARG271 |
| B | HIS272 |
| B | HOH856 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 505 |
| Chain | Residue |
| B | LYS90 |
| B | PRO96 |
| B | ALA97 |
| B | HOH904 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 506 |
| Chain | Residue |
| B | GLY286 |
| B | GLU288 |
| B | ARG290 |
| B | HOH974 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EPE B 507 |
| Chain | Residue |
| B | TYR82 |
| B | GLY83 |
| B | GLY84 |
| B | TRP92 |
| B | HOH972 |
