4J5R
TARG1 (C6orf130), Terminal ADP-ribose Glycohydrolase 1 bound to ADP-HPD
Summary for 4J5R
Entry DOI | 10.2210/pdb4j5r/pdb |
Related | 4J5Q 4J5S |
Descriptor | O-acetyl-ADP-ribose deacetylase 1, 5'-O-[(S)-{[(S)-{[(2R,3R,4S)-3,4-DIHYDROXYPYRROLIDIN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]ADENOSINE, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | dna repair, cellular signaling, macro domain, glycohydrolase, poly-adp ribose, parp, adp-ribose, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 34403.66 |
Authors | Schellenberg, M.J.,Appel, C.D.,Krahn, J.,Williams, R.S. (deposition date: 2013-02-09, release date: 2013-03-27, Last modification date: 2023-09-20) |
Primary citation | Sharifi, R.,Morra, R.,Appel, C.D.,Tallis, M.,Chioza, B.,Jankevicius, G.,Simpson, M.A.,Matic, I.,Ozkan, E.,Golia, B.,Schellenberg, M.J.,Weston, R.,Williams, J.G.,Rossi, M.N.,Galehdari, H.,Krahn, J.,Wan, A.,Trembath, R.C.,Crosby, A.H.,Ahel, D.,Hay, R.,Ladurner, A.G.,Timinszky, G.,Williams, R.S.,Ahel, I. Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease. Embo J., 32:1225-1237, 2013 Cited by PubMed: 23481255DOI: 10.1038/emboj.2013.51 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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