4J4P
The complex of human IgE-Fc with two bound Fab fragments
Summary for 4J4P
Entry DOI | 10.2210/pdb4j4p/pdb |
Related | 1LSO 2WQR 2Y7Q |
Descriptor | Ig epsilon chain C region, Immunoglobulin G Fab Fragment Heavy Chain, Immunoglobulin G Fab Fragment Light Chain, ... (5 entities in total) |
Functional Keywords | ig like domain, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 6 |
Total formula weight | 177746.06 |
Authors | Drinkwater, N.,Sutton, B.J. (deposition date: 2013-02-07, release date: 2014-03-12, Last modification date: 2020-07-29) |
Primary citation | Drinkwater, N.,Cossins, B.P.,Keeble, A.H.,Wright, M.,Cain, K.,Hailu, H.,Oxbrow, A.,Delgado, J.,Shuttleworth, L.K.,Kao, M.W.,McDonnell, J.M.,Beavil, A.J.,Henry, A.J.,Sutton, B.J. Human immunoglobulin E flexes between acutely bent and extended conformations. Nat.Struct.Mol.Biol., 21:397-404, 2014 Cited by PubMed: 24632569DOI: 10.1038/nsmb.2795 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
Download full validation report