4J21
Tankyrase 2 in complex with 7-(4-amino-2-chlorophenyl)-4-methylquinolin-2(1H)-one
Summary for 4J21
Entry DOI | 10.2210/pdb4j21/pdb |
Related | 3W51 4IUE 4J1Z 4J22 |
Descriptor | Tankyrase-2, ZINC ION, SULFATE ION, ... (5 entities in total) |
Functional Keywords | ribosylation, transferase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9H2K2 |
Total number of polymer chains | 1 |
Total formula weight | 24535.47 |
Authors | Jansson, A.E.,Larsson, E.A.,Nordlund, P.L. (deposition date: 2013-02-04, release date: 2013-06-26, Last modification date: 2023-11-08) |
Primary citation | Larsson, E.A.,Jansson, A.E.,Ng, F.M.,Then, S.W.,Panicker, R.,Liu, B.,Sangthongpitag, K.,Pendharkar, V.,Tai, S.J.,Hill, J.,Dan, C.,Ho, S.Y.,Cheong, W.W.,Poulsen, A.,Blanchard, S.,Lin, G.R.,Alam, J.,Keller, T.H.,Nordlund, P. Fragment-based ligand design of novel potent inhibitors of tankyrases. J.Med.Chem., 56:4497-4508, 2013 Cited by PubMed: 23672613DOI: 10.1021/jm400211f PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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