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4J21

Tankyrase 2 in complex with 7-(4-amino-2-chlorophenyl)-4-methylquinolin-2(1H)-one

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tankyrase-2polymer21023993.21UniProt (Q9H2K2)
Pfam (PF00644)
Homo sapiens (human)TANK2, ADP-ribosyltransferase diphtheria toxin-like 6, ARTD6, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C, D
(A)
SULFATE IONnon-polymer96.12Chemie (SO4)
4E
(A)
7-(4-amino-2-chlorophenyl)-4-methylquinolin-2(1H)-onenon-polymer284.71Chemie (AJ6)
5F
(A)
waterwater18.0214Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23993.2
Non-Polymers*Number of molecules4
Total formula weight542.3
All*Total formula weight24535.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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