4J18

Crystal structure of H191L mutant of UDP-glucose pyrophosphorylase from Leishmania major

Summary for 4J18

Entry DOI	10.2210/pdb4j18/pdb
Related	2OEF 2OEG 4EUJ 4EVK
Descriptor	UDP-glucose pyrophosphorylase (2 entities in total)
Functional Keywords	rossmann-like alpha/beta/alpha sandwich fold of catalytic domain, nucleotidyltransferase, utp, glc-1-p, transferase
Biological source	Leishmania major
Total number of polymer chains	1
Total formula weight	56029.78
Authors	Fuehring, J.I.,Routier, F.H.,Lamerz, A.-C.,Baruch, P.,Gerardy-Schahn, R.,Fedorov, R. (deposition date: 2013-02-01, release date: 2014-01-29, Last modification date: 2023-09-20)
Primary citation	Fuehring, J.I.,Routier, F.H.,Lamerz, A.-C.,Baruch, P.,Gerardy-Schahn, R.,Fedorov, R. Catalytic Mechanism and Allosteric Regulation of UDP-Glucose Pyrophosphorylase from Leishmania major ACS CATALYSIS, 3:2976-2985, 2013 Cited by DOI: 10.1021/cs4007777 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation