4IYE
Crystal structure of AdTx1 (rho-Da1a) from eastern green mamba (Dendroaspis angusticeps)
Summary for 4IYE
Entry DOI | 10.2210/pdb4iye/pdb |
Related | 1FF4 2H5F 2H7Z 2VLW 3FEV 3NEQ 4DO8 |
Descriptor | Toxin AdTx1, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (4 entities in total) |
Functional Keywords | snake three-finger toxin family, type a muscarinic toxin subfamily, allosteric antagonist of the alpha-1a adrenergic receptor (adra1a), acts as a relaxant of smooth muscle, alpha-1a adrenergic receptor, g-rhoda1a k34a, expressed by the venom gland, toxin |
Biological source | Dendroaspis angusticeps (Eastern green mamba) |
Cellular location | Secreted: P85092 |
Total number of polymer chains | 1 |
Total formula weight | 7574.58 |
Authors | Stura, E.A.,Vera, L.,Maiga, A.A.,Marchetti, C.,Lorphelin, A.,Bellanger, L.,Servant, D.,Gilles, N. (deposition date: 2013-01-28, release date: 2013-05-08, Last modification date: 2023-09-20) |
Primary citation | Maiga, A.,Vera, L.,Marchetti, C.,Lorphelin, A.,Bellanger, L.,Mourier, G.,Servent, D.,Gilles, N.,Stura, E.A. Crystallization of recombinant green mamba rho-Da1a toxin during a lyophilization procedure and its structure determination. Acta Crystallogr.,Sect.F, 69:704-709, 2013 Cited by PubMed: 23722859DOI: 10.1107/S1744309113011470 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.951 Å) |
Structure validation
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