4ISO
Crystal Structure of Matriptase in complex with its inhibitor HAI-1
Summary for 4ISO
Entry DOI | 10.2210/pdb4iso/pdb |
Related | 4IS5 4ISL 4ISN |
Descriptor | Suppressor of tumorigenicity 14 protein, Kunitz-type protease inhibitor 1, GLUTATHIONE, ... (7 entities in total) |
Functional Keywords | beta barrel, serine protease, inhibitor, epithelium, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane ; Single-pass type II membrane protein : Q9Y5Y6 Secreted: O43278 |
Total number of polymer chains | 2 |
Total formula weight | 34485.77 |
Authors | Huang, M.D.,Zhao, B.Y.,Yuan, C.,Li, R. (deposition date: 2013-01-16, release date: 2013-03-06, Last modification date: 2023-09-20) |
Primary citation | Zhao, B.,Yuan, C.,Li, R.,Qu, D.,Huang, M.,Ngo, J.C. Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1. J.Biol.Chem., 288:11155-11164, 2013 Cited by PubMed: 23443661DOI: 10.1074/jbc.M113.454611 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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