Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GSH A 301 |
| Chain | Residue |
| A | TRP29 |
| A | TYR114 |
| A | ARG119 |
| A | PRO120 |
| A | CYS122 |
| A | ARG206 |
| A | ILE207 |
| A | HOH462 |
| A | HOH535 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 302 |
| Chain | Residue |
| A | PHE130 |
| A | VAL162 |
| A | ILE163 |
| A | GLN164 |
| A | GLN165 |
| A | MET181 |
| A | ARG230 |
| A | HOH447 |
| B | GLU272 |
| B | HOH531 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GOL A 303 |
| Chain | Residue |
| A | HIS57 |
| A | CYS58 |
| A | TYR59 |
| A | ILE60 |
| A | ASP60 |
| A | TYR60 |
| A | HOH472 |
| B | PHE263 |
| B | ARG265 |
| B | TYR280 |
| B | GLY282 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 304 |
| Chain | Residue |
| A | LEU36 |
| A | THR65 |
| A | ARG84 |
| A | HOH460 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PEG A 305 |
| Chain | Residue |
| A | ASP23 |
| A | GLU24 |
| A | GLY25 |
| A | GLU26 |
| A | TRP27 |
| A | PRO28 |
| A | HIS71 |
| A | MET117 |
| A | LEU155 |
| A | HOH465 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PGE A 306 |
| Chain | Residue |
| A | SER186 |
| A | GLY187 |
| A | ALA221 |
| A | GLN221 |
| A | ARG222 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG B 401 |
| Chain | Residue |
| A | LEU36 |
| A | GLY37 |
| B | LEU291 |
| B | ARG292 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG B 402 |
| Chain | Residue |
| B | GLY285 |
| B | LYS287 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLS |
| Chain | Residue | Details |
| A | ASP189-SER200 | |
| site_id | PS00280 |
| Number of Residues | 19 |
| Details | BPTI_KUNITZ_1 Pancreatic trypsin inhibitor (Kunitz) family signature. FvyGGClgnknnYlreeeC |
| Chain | Residue | Details |
| B | PHE278-CYS296 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Reactive bond => ECO:0000250 |
| Chain | Residue | Details |
| B | ARG260 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN164 | |
