4IS3
Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution
Summary for 4IS3
Entry DOI | 10.2210/pdb4is3/pdb |
Related | 4IS2 |
Descriptor | Bile acid 3-alpha hydroxysteroid dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UNKNOWN LIGAND, ... (5 entities in total) |
Functional Keywords | nad(p)-binding rossmann-fold domains, structural genomics, joint center for structural genomics, jcsg, protein structure initiative, psi-biology, oxidoreductase |
Biological source | Clostridium scindens |
Total number of polymer chains | 4 |
Total formula weight | 120151.32 |
Authors | Joint Center for Structural Genomics (JCSG) (deposition date: 2013-01-16, release date: 2013-04-24, Last modification date: 2023-02-01) |
Primary citation | Joint Center for Structural Genomics (JCSG) Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution To be published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report