4IRU
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Summary for 4IRU
Entry DOI | 10.2210/pdb4iru/pdb |
Descriptor | LepB, Ras-related protein Rab-1A, ACETATE ION, ... (9 entities in total) |
Functional Keywords | arginine finger, glutamate finger, p-loop motif, nucleotide binding, intrinsic gtpase activity, gtp hydrolysis, gtp hydrolysis activator, gtpase activating protein (gap), protein transport, hydrolase-hydrolase complex, hydrolase/hydrolase |
Biological source | Legionella pneumophila More |
Cellular location | Golgi apparatus: P62820 |
Total number of polymer chains | 6 |
Total formula weight | 168608.75 |
Authors | Mishra, A.K.,Delcampo, C.M.,Collins, R.E.,Roy, C.R.,Lambright, D.G. (deposition date: 2013-01-15, release date: 2013-07-10, Last modification date: 2013-09-04) |
Primary citation | Mishra, A.K.,Del Campo, C.M.,Collins, R.E.,Roy, C.R.,Lambright, D.G. The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism. J.Biol.Chem., 288:24000-24011, 2013 Cited by PubMed: 23821544DOI: 10.1074/jbc.M113.470625 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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