4IRP

Crystal structure of catalytic domain of human beta1,4-galactosyltransferase-7 in open conformation with manganses and UDP

Summary for 4IRP

Entry DOI	10.2210/pdb4irp/pdb
Related	4IRQ
Descriptor	Beta-1,4-galactosyltransferase 7, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... (6 entities in total)
Functional Keywords	gt-a fold, open conformation, manganese and udp complex, glycosyltransferase, golgi, transferase
Biological source	Homo sapiens (human)
Cellular location	Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein: Q9UBV7
Total number of polymer chains	2
Total formula weight	59774.09
Authors	Tsutsui, Y.,Ramakrishnan, B.,Qasba, P.K. (deposition date: 2013-01-15, release date: 2013-09-25, Last modification date: 2023-09-20)
Primary citation	Tsutsui, Y.,Ramakrishnan, B.,Qasba, P.K. Crystal Structures of beta-1,4-Galactosyltransferase 7 Enzyme Reveal Conformational Changes and Substrate Binding. J.Biol.Chem., 288:31963-31970, 2013 Cited by PubMed: 24052259 DOI: 10.1074/jbc.M113.509984 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation