4IMZ

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

4IMZ の概要

• エントリーDOI: 10.2210/pdb4imz/pdb
• 関連するPDBエントリー: 4IMQ 4IN2 4INH 4IRO
• 関連するBIRD辞書のPRD_ID: PRD_001061
• 分子名称: Genome polyprotein, peptide inhibitor, syc 10, THIOCYANATE ION, ... (5 entities in total)
• 機能のキーワード: protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Norovirus Hu/1968/US (Hu/NV/NV/1968/US); 詳細
• 細胞内の位置: Protein p48: Host membrane; Single-pass membrane protein (Potential). NTPase: Host membrane; Single-pass membrane protein (Potential). Protein p22: Host membrane; Single-pass membrane protein (Potential): Q83883
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 20238.76

構造登録者

Prasad, B.V.V.,Muhaxhiri, Z.,Deng, L.,Shanker, S.,Sankaran, B.,Estes, M.K.,Palzkill, T.,Song, Y. (登録日: 2013-01-03, 公開日: 2013-02-20, 最終更新日: 2013-04-10)

• 主引用文献: Muhaxhiri, Z.,Deng, L.,Shanker, S.,Sankaran, B.,Estes, M.K.,Palzkill, T.,Song, Y.,Prasad, B.V.; Structural basis of substrate specificity and protease inhibition in norwalk virus.; J.Virol., 87:4281-4292, 2013; PubMed: 23365454; DOI: 10.1128/JVI.02869-12

実験手法

X-RAY DIFFRACTION (1.7 Å)