4IMZ
Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SCN A 201 |
| Chain | Residue |
| A | PRO2 |
| A | THR4 |
| A | LEU5 |
| A | ARG8 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE NA A 202 |
| Chain | Residue |
| A | LYS0 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SCN A 203 |
| Chain | Residue |
| A | HOH344 |
| A | HOH366 |
| A | HOH389 |
| A | VAL82 |
| A | SER84 |
| A | HIS145 |
| A | LYS146 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SCN A 204 |
| Chain | Residue |
| A | HIS50 |
| A | GLN172 |
| A | ALA173 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SCN A 205 |
| Chain | Residue |
| A | LYS37 |
| A | HOH369 |
| A | HOH403 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"description":"For 3CLpro activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU00870","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16641296","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23365454","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Cleavage; by 3CLpro","evidences":[{"source":"PubMed","id":"17554035","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"20976190","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
