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4IMZ

Structural Basis of Substrate Specificity and Protease Inhibition in Norwalk Virus

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Genome polyproteinpolymer18319410.31UniProt (Q83883)Norovirus Hu/1968/US (Hu/NV/NV/1968/US)Protein p48, NTPase, p41, Protein p22, Viral genome-linked protein, VPG, 3C-like protease, 3CLpro, Calicivirin, RNA-directed RNA polymerase, RdRp
2B
(B)
peptide inhibitor, syc 10polymer4573.11BIRD (PRD_001061)synthetic construct
3C, E, F, G
(A)
THIOCYANATE IONnon-polymer58.14Chemie (SCN)
4D
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
5H, I
(A, B)
waterwater18.0220Chemie (HOH)
Sequence modifications
A: 1 - 181 (UniProt: Q83883)
PDBExternal DatabaseDetails
Asp -1-expression tag
Lys 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight19983.4
Non-Polymers*Number of molecules5
Total formula weight255.3
All*Total formula weight20238.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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