4IFD
Crystal structure of an 11-subunit eukaryotic exosome complex bound to RNA
Summary for 4IFD
Entry DOI | 10.2210/pdb4ifd/pdb |
Descriptor | Exosome complex component RRP45, Exosome complex exonuclease DIS3, Exosome complex exonuclease RRP6, ... (18 entities in total) |
Functional Keywords | exosome, rna, rrp44, dis3, pin, rrp6, exonuclease, endonuclease, hydrolase, nuclease, ribonuclease, rna processing, hydrolase-rna complex, hydrolase/rna |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Cellular location | Cytoplasm : Q05636 Q08162 P46948 P25359 P53256 Q12277 P48240 Q08285 P38792 P53859 Nucleus, nucleolus : Q12149 |
Total number of polymer chains | 12 |
Total formula weight | 438162.46 |
Authors | Makino, D.L.,Conti, E. (deposition date: 2012-12-14, release date: 2013-02-06, Last modification date: 2023-11-08) |
Primary citation | Makino, D.L.,Baumgartner, M.,Conti, E. Crystal structure of an RNA-bound 11-subunit eukaryotic exosome complex. Nature, 495:70-75, 2013 Cited by PubMed: 23376952DOI: 10.1038/nature11870 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.805 Å) |
Structure validation
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