4ICY
Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE
Summary for 4ICY
Entry DOI | 10.2210/pdb4icy/pdb |
Related | 2QA1 |
Descriptor | Polyketide oxygenase PgaE, FLAVIN-ADENINE DINUCLEOTIDE, 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | fad-dependent aromatic hydroxylation, monooxygenase, fad, oxidoreductase |
Biological source | Streptomyces sp. PGA64 |
Total number of polymer chains | 1 |
Total formula weight | 55104.60 |
Authors | Kallio, P.,Patrikainen, P.,Belogurov, G.,Mantsala, P.,Yang, K.,Niemi, J.,Metsa-Ketela, M. (deposition date: 2012-12-11, release date: 2013-06-12, Last modification date: 2024-04-03) |
Primary citation | Kallio, P.,Patrikainen, P.,Belogurov, G.A.,Mantsala, P.,Yang, K.,Niemi, J.,Metsa-Ketela, M. Tracing the Evolution of Angucyclinone Monooxygenases: Structural Determinants for C-12b Hydroxylation and Substrate Inhibition in PgaE. Biochemistry, 52:4507-4516, 2013 Cited by PubMed: 23731237DOI: 10.1021/bi400381s PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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