4IAK

Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20

4IAK の概要

• エントリーDOI: 10.2210/pdb4iak/pdb
• 関連するPDBエントリー: 4IAC 4IAD 4IAF 4IAI 4IAY 4IAZ 4IB0 4IB1 4IB3
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, phosphorylated pseudo-substrate peptide pSP20, STRONTIUM ION, ... (6 entities in total)
• 機能のキーワード: kinase enzyme, phosphotransfer, phosphorylation, transferase-peptide complex, transferase/peptide
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Cytoplasm. Isoform 2: Cell projection, cilium, flagellum (By similarity): P05132
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44507.99

構造登録者

Gerlits, O.,Kovalevsky, A. (登録日: 2012-12-06, 公開日: 2013-06-12, 最終更新日: 2013-12-18)

• 主引用文献: Gerlits, O.,Waltman, M.J.,Taylor, S.,Langan, P.,Kovalevsky, A.; Insights into the Phosphoryl Transfer Catalyzed by cAMP-Dependent Protein Kinase: An X-ray Crystallographic Study of Complexes with Various Metals and Peptide Substrate SP20.; Biochemistry, 52:3721-3727, 2013; PubMed: 23672593; DOI: 10.1021/bi400066a

実験手法

X-RAY DIFFRACTION (1.6 Å)