4IAK

Low temperature X-ray structure of cAMP dependent protein kinase A in complex with high Sr2+ concentration, ADP and phosphorylated peptide pSP20

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	cAMP-dependent protein kinase catalytic subunit alpha	polymer	356	41566.2	1	UniProt (P05132) Pfam (PF00069) In PDB	Mus musculus (mouse)	PKA C-alpha
2	S	phosphorylated pseudo-substrate peptide pSP20	polymer	20	2279.4	1	UniProt (by SIFTS) (P61925) In PDB	Homo sapiens
3	A	STRONTIUM ION	non-polymer		87.6	2	Chemie (SR)
4	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
5	A	CARBONATE ION	non-polymer		60.0	1	Chemie (CO3)
6		water	water		18.0	284	Chemie (HOH)

Sequence modifications

A: 1 - 350 (UniProt: P05132)

PDB	External Database	Details
His -5	-	EXPRESSION TAG
His -4	-	EXPRESSION TAG
His -3	-	EXPRESSION TAG
His -2	-	EXPRESSION TAG
His -1	-	EXPRESSION TAG
His 0	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	43845.5
Non-Polymers*	Number of molecules	4
	Total formula weight	662.5
All*	Total formula weight	44508.0

*Water molecules are not included.