4I9V

The atomic structure of 5-Hydroxymethyl 2'-deoxycitidine base paired with 2'-deoxyguanosine in Dickerson Drew Dodecamer

Summary for 4I9V

• Entry DOI: 10.2210/pdb4i9v/pdb
• Related: 355D
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5HC)P*GP*CP*G)-3'), MAGNESIUM ION, SPERMINE (FULLY PROTONATED FORM), ... (4 entities in total)
• Functional Keywords: 5-hydroxymethyl 2' deoxycitidine, 5-hydroxymethyl-dc adduct, modified ddd, dodecamer of b-dna, dna
• Biological source: Synthetic DNA
• Total number of polymer chains: 2
• Total formula weight: 7823.89

Authors

Nocek, B.,Szulik, M.W.,Joachimiak, A.,Stone, M.P. (deposition date: 2012-12-05, release date: 2013-11-20, Last modification date: 2023-09-20)

• Primary citation: Szulik, M.W.,Pallan, P.S.,Nocek, B.,Voehler, M.,Banerjee, S.,Brooks, S.,Joachimiak, A.,Egli, M.,Eichman, B.F.,Stone, M.P.; Differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine.; Biochemistry, 54:1294-1305, 2015; PubMed: 25632825; DOI: 10.1021/bi501534x

Experimental method

X-RAY DIFFRACTION (1.02 Å)