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4I6L

Crystal structure of OTUB1 in complex with ubiquitin variant

Summary for 4I6L
Entry DOI10.2210/pdb4i6l/pdb
DescriptorUbiquitin thioesterase OTUB1, Ubiquitin (3 entities in total)
Functional Keywordsdeubiquitinase, hydrolase
Biological sourceHomo sapiens (human)
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Cellular locationCytoplasm (By similarity): Q96FW1
Ubiquitin: Cytoplasm (By similarity): P0CG48
Total number of polymer chains2
Total formula weight35332.88
Authors
Juang, Y.C.,Sicheri, F. (deposition date: 2012-11-29, release date: 2013-01-16, Last modification date: 2023-09-20)
Primary citationErnst, A.,Avvakumov, G.,Tong, J.,Fan, Y.,Zhao, Y.,Alberts, P.,Persaud, A.,Walker, J.R.,Neculai, A.M.,Neculai, D.,Vorobyov, A.,Garg, P.,Beatty, L.,Chan, P.K.,Juang, Y.C.,Landry, M.C.,Yeh, C.,Zeqiraj, E.,Karamboulas, K.,Allali-Hassani, A.,Vedadi, M.,Tyers, M.,Moffat, J.,Sicheri, F.,Pelletier, L.,Durocher, D.,Raught, B.,Rotin, D.,Yang, J.,Moran, M.F.,Dhe-Paganon, S.,Sidhu, S.S.
A strategy for modulation of enzymes in the ubiquitin system.
Science, 339:590-595, 2013
Cited by
PubMed: 23287719
DOI: 10.1126/science.1230161
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.488 Å)
Structure validation

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건을2024-03-27부터공개중

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