4I6L
Crystal structure of OTUB1 in complex with ubiquitin variant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ubiquitin thioesterase OTUB1 | polymer | 229 | 26572.8 | 1 | UniProt (Q96FW1) Pfam (PF10275) | Homo sapiens (human) | Deubiquitinating enzyme OTUB1, OTU domain-containing ubiquitin aldehyde-binding protein 1, Otubain-1, hOTU1, Ubiquitin-specific-processing protease OTUB1 |
| 2 | B (B) | Ubiquitin | polymer | 76 | 8760.1 | 1 | UniProt (P0CG48) Pfam (PF00240) | Homo sapiens (human) | Ubiquitin |
| 3 | C, D (A, B) | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A: 45 - 271 (UniProt: Q96FW1)
B: 1 - 74 (UniProt: P0CG48)
| PDB | External Database | Details |
|---|---|---|
| Gly 43 | - | expression tag |
| Ser 44 | - | expression tag |
| Ser 91 | Cys 91 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Lys 42 | Arg 118 | variant |
| Leu 44 | Ile 120 | variant |
| Arg 47 | Gly 123 | variant |
| His 62 | Gln 138 | variant |
| Phe 66 | Thr 142 | variant |
| Tyr 68 | His 144 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 35332.9 | |
| All* | Total formula weight | 35332.9 |
