4I1N

R104A-ca1697 nanobody binding to the binary DHFR.folate complex

Summary for 4I1N

• Entry DOI: 10.2210/pdb4i1n/pdb
• Related: 4I13
• Descriptor: Dihydrofolate reductase, Protein ca1697 (nanobody), FOLIC ACID, ... (4 entities in total)
• Functional Keywords: alpha/beta fold, immunoglobulin fold, reductase, nadph, folate derivatives, hydride transfer, oxidoreductase-immune system complex, oxidoreductase/immune system
• Biological source: Escherichia coli; More
• Total number of polymer chains: 2
• Total formula weight: 33201.23

Authors

Oyen, D.,Steyaert, J.,Barlow, J.N. (deposition date: 2012-11-21, release date: 2013-11-27)

• Primary citation: Oyen, D.,Steyaert, J.,Barlow, J.N.; Exploring an alternative antibody interaction mechanism; To be Published,

Experimental method

X-RAY DIFFRACTION (1.888 Å)