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4I0C

The structure of the camelid antibody cAbHuL5 in complex with human lysozyme

Summary for 4I0C
Entry DOI10.2210/pdb4i0c/pdb
DescriptorLysozyme C, cAbHuL5 antibody, CHLORIDE ION, ... (5 entities in total)
Functional Keywordsbeta-barrel, alpha-beta protein, immune recognition, glycosidase, immune system-hydrolase complex, immune system/hydrolase
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted: P61626
Total number of polymer chains4
Total formula weight59077.95
Authors
Primary citationDe Genst, E.,Chan, P.H.,Pardon, E.,Hsu, S.T.,Kumita, J.R.,Christodoulou, J.,Menzer, L.,Chirgadze, D.Y.,Robinson, C.V.,Muyldermans, S.,Matagne, A.,Wyns, L.,Dobson, C.M.,Dumoulin, M.
A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.
J.Phys.Chem.B, 117:13245-13258, 2013
Cited by
PubMed: 23919586
DOI: 10.1021/jp403425z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.95 Å)
Structure validation

217705

數據於2024-03-27公開中

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