4I0C
The structure of the camelid antibody cAbHuL5 in complex with human lysozyme
Summary for 4I0C
Entry DOI | 10.2210/pdb4i0c/pdb |
Descriptor | Lysozyme C, cAbHuL5 antibody, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | beta-barrel, alpha-beta protein, immune recognition, glycosidase, immune system-hydrolase complex, immune system/hydrolase |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P61626 |
Total number of polymer chains | 4 |
Total formula weight | 59077.95 |
Authors | De Genst, E.,Chan, P.H.,Pardon, E.,Kumita, J.R.,Christodoulou, J.,Menzer, L.,Chirgadze, D.Y.,Robinson, C.V.,Muyldermans, S.,Matagne, A.,Wyns, L.,Dobson, C.M.,Dumoulin, M. (deposition date: 2012-11-16, release date: 2013-10-09, Last modification date: 2013-11-06) |
Primary citation | De Genst, E.,Chan, P.H.,Pardon, E.,Hsu, S.T.,Kumita, J.R.,Christodoulou, J.,Menzer, L.,Chirgadze, D.Y.,Robinson, C.V.,Muyldermans, S.,Matagne, A.,Wyns, L.,Dobson, C.M.,Dumoulin, M. A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation. J.Phys.Chem.B, 117:13245-13258, 2013 Cited by PubMed: 23919586DOI: 10.1021/jp403425z PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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