4I0C

The structure of the camelid antibody cAbHuL5 in complex with human lysozyme

4I0C の概要

• エントリーDOI: 10.2210/pdb4i0c/pdb
• 分子名称: Lysozyme C, cAbHuL5 antibody, CHLORIDE ION, ... (5 entities in total)
• 機能のキーワード: beta-barrel, alpha-beta protein, immune recognition, glycosidase, immune system-hydrolase complex, immune system/hydrolase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P61626
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 59077.95

構造登録者

De Genst, E.,Chan, P.H.,Pardon, E.,Kumita, J.R.,Christodoulou, J.,Menzer, L.,Chirgadze, D.Y.,Robinson, C.V.,Muyldermans, S.,Matagne, A.,Wyns, L.,Dobson, C.M.,Dumoulin, M. (登録日: 2012-11-16, 公開日: 2013-10-09, 最終更新日: 2013-11-06)

• 主引用文献: De Genst, E.,Chan, P.H.,Pardon, E.,Hsu, S.T.,Kumita, J.R.,Christodoulou, J.,Menzer, L.,Chirgadze, D.Y.,Robinson, C.V.,Muyldermans, S.,Matagne, A.,Wyns, L.,Dobson, C.M.,Dumoulin, M.; A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation.; J.Phys.Chem.B, 117:13245-13258, 2013; PubMed: 23919586; DOI: 10.1021/jp403425z

実験手法

X-RAY DIFFRACTION (1.95 Å)